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Similar content being viewed by others Introduction B cells regulate many functions required for immune homeostasis and can present antigens very efficiently through their major histocompatibility complexes to T cells 1,2

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Protection of ovarian function Currently, fertility preservation efforts before treatment with cyclophosphamide, including oocyte, embryo, and ovarian cortex cryopreservation, have aided in those achieving pregnancy post-treatment [87,88,89]